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ADENTRI™ (adenosine A1 antagonist)
In 1997, Biogen began a collaboration with CV Therapeutics of Palo Alto, California, to develop and market an A1 Adenosine Receptor Antagonist as a treatment for acute and chronic congestive heart failure (CHF), is in Phase II trials. The agent works by blocking a receptor located in the kidney, resulting in the protection of kidney function and the excretion of sodium and fluid.

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