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Products & Pipeline

Products & Pipeline

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Product Pipeline

Research Preclinical Phase I Phase II Phase III Regulatory Filing Approved Phase IV
AVONEX® (Interferon beta-1a)
MS-Open Label
MS-Monosymptomatic (CHAMPS)
MS-Secondary Progressive
MS-Combination Trials
AMEVIVE® (alefacept)
Psoriasis
ANTEGREN® (natalizumab)
MS
Crohn's disease
ADENTRI™ (adenosine A1 antagonist)
Congestive heart failure
Lymphotoxin Beta Receptor
Autoimmune diseases
Interferon Beta Gene Delivery
Cancer indications
VLA-1 mAb
Inflammation and Fibrosis
VLA-4 Inhibitor
Inflammation
LTBR mAb
Solid tumors

ADENTRI™ (adenosine A1 antagonist)

In 1997, Biogen began a collaboration with CV Therapeutics of Palo Alto, California, to develop and market an A1 Adenosine Receptor Antagonist as a treatment for acute and chronic congestive heart failure (CHF), is in Phase II trials. The agent works by blocking a receptor located in the kidney, resulting in the protection of kidney function and the excretion of sodium and fluid.


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