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Product Pipeline

Research Preclinical Phase I Phase II Phase III Regulatory Filing Approved Phase IV
AVONEX® (Interferon beta-1a)
MS-Open Label
MS-Monosymptomatic (CHAMPS)
MS-Secondary Progressive
MS-Combination Trials
AMEVIVE® (alefacept)
Psoriasis
ANTEGREN® (natalizumab)
MS
Crohn's disease
ADENTRI™ (adenosine A1 antagonist)
Congestive heart failure
Lymphotoxin Beta Receptor
Autoimmune diseases
Interferon Beta Gene Delivery
Cancer indications
VLA-1 mAb
Inflammation and Fibrosis
VLA-4 Inhibitor
Inflammation
LTBR mAb
Solid tumors

LTBR mAb

Anti-lymphotoxin beta receptor (LTBR) monoclonal antibody. LTBR is a member of the TNF superfamily of cytokines. The activation of LTBR has been demonstrated to inhibit tumor growth in animal models. An agonist antibody against this target has been generated.


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